Protective effects of CCL01 against Aβ-induced neurotoxicity in 5xFAD transgenic mouse model of Alzheimer's disease

Protective effects of CCL01 against Aβ-induced neurotoxicity in 5xFAD transgenic mouse model of Alzheimer's disease

Alzheimer’s disease (AD) is the most common dementia characterized by the excessive accumulation of amyloid-beta (Aβ) and tau aggregates, as well as neuronal damage and neuroinflammation. Metabolic disruption in AD has been noticed because metabolite alterations closely correlate with Aβ neuropathol...

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Bibliographic Details
Main Authors: In Gyoung Ju, Su Young Son, Seungmin Lee, Hyeri Im, Eugene Huh, Hyeyoon Eo, Jin Gyu Choi, Mi Won Sohn, Sung-Vin Yim, Sun Yeou Kim, Dong-Hyun Kim, Choong Hwan Lee, Myung Sook Oh
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Alzheimer’s disease
5xFAD
Cuscuta seeds
Lactobacillus paracasei
Tau phosphorylation
Metabolic disruption
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222014949

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http://www.sciencedirect.com/science/article/pii/S0753332222014949

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