Double-Stranded RNA Dependent Kinase R Regulates Antibacterial Immunity in Sepsis
Double-stranded RNA dependent kinase R (PKR) is originally identified as an intracellular sensor of viral infection, but its role in bacterial infection remains largely unknown. Here we report that PKR was an important regulator of antibacterial immunity in sepsis. Genetic deletion of PKR or pharmac...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Karger Publishers
2020-12-01
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Series: | Journal of Innate Immunity |
Subjects: | |
Online Access: | https://www.karger.com/Article/FullText/507932 |