Mining Xanthine Oxidase Inhibitors from an Edible Seaweed <i>Pterocladiella capillacea</i> by Using In Vitro Bioassays, Affinity Ultrafiltration LC-MS/MS, Metabolomics Tools, and In Silico Prediction

Mining Xanthine Oxidase Inhibitors from an Edible Seaweed <i>Pterocladiella capillacea</i> by Using In Vitro Bioassays, Affinity Ultrafiltration LC-MS/MS, Metabolomics Tools, and In Silico Prediction

The prevalence of gout and the adverse effects of current synthetic anti-gout drugs call for new natural and effective xanthine oxidase (XOD) inhibitors to target this disease. Based on our previous finding that an edible seaweed <i>Pterocladiella capillacea</i> extract inhibits XOD, XOD...

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Bibliographic Details
Main Authors: Yawen Wang, Longjian Zhou, Minqi Chen, Yayue Liu, Yu Yang, Tiantian Lu, Fangfang Ban, Xueqiong Hu, Zhongji Qian, Pengzhi Hong, Yi Zhang
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Marine Drugs
Subjects:
<i>Pterocladiella capillacea</i>
xanthine oxidase inhibitors
anti-inflammatory
affinity ultrafiltration LC-MS/MS
molecular networking
Online Access:https://www.mdpi.com/1660-3397/21/10/502

Internet

https://www.mdpi.com/1660-3397/21/10/502

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