Role of MCPIP1 in the Endothelial-Mesenchymal Transition Induced by Silica

Role of MCPIP1 in the Endothelial-Mesenchymal Transition Induced by Silica

Background: Silicosis is characterized by the accumulation of fibroblasts and the excessive deposition of extracellular matrix. Fibroblast generation via endothelial-mesenchymal transition (EndMT) is one process responsible for this accumulation of fibroblasts. However, the mechanisms underlying End...

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Bibliographic Details
Main Authors: Jie Chao, Xingang Wang, Yuxia Zhang, Tiebing Zhu, Wei Zhang, Zewei Zhou, Jian Yang, Bing Han, Yusi Cheng, Xiaojie Tu, Honghong Yao
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Endothelial-mesenchymal transition
MCPIP1
Silicosis
Fibrosis
Autophagy
Online Access:http://www.karger.com/Article/FullText/452547

Internet

http://www.karger.com/Article/FullText/452547

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