Angiogenesis effect of udenafil in a caveolin-1 deficient moyamoya disease model: A pre-clinical animal study

Purpose Although pathogenic mechanisms of moyamoya disease (MMD) remain unknown, recent studies suggest that it is a caveolae disease. This study evaluated the effect of udenafil, a phosphodiesterase-5 inhibitor, on angiogenesis in in vitro and in vivo MMD models. Methods Angiogenesis and vessel mat...

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Bibliographic Details
Main Authors: Dong Hee Kim, Jeong Pyo Son, Yeon Hee Cho, Eun Hee Kim, Gyeong Joon Moon, Oh Young Bang
Format: Article
Language:English
Published: Sungkyunkwan University School of Medi 2023-03-01
Series:Precision and Future Medicine
Subjects:
Online Access:http://pfmjournal.org/upload/pdf/pfm-2022-00135.pdf