The Skin-Whitening Effects of Ectoine via the Suppression of α-MSH-Stimulated Melanogenesis and the Activation of Antioxidant Nrf2 Pathways in UVA-Irradiated Keratinocytes

The Skin-Whitening Effects of Ectoine via the Suppression of α-MSH-Stimulated Melanogenesis and the Activation of Antioxidant Nrf2 Pathways in UVA-Irradiated Keratinocytes

Ultraviolet A (UVA)-irradiation induced reactive oxygen species (ROS) production mediates excessive melanogenesis in skin cells leading to pigmentation. We demonstrated the depigmenting and anti-melanogenic effects of Ectoine, a natural bacterial osmolyte, in UVA-irradiated human (HaCaT) keratinocyt...

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Bibliographic Details
Main Authors: You-Cheng Hseu, Xuan-Zao Chen, Yugandhar Vudhya Gowrisankar, Hung-Rong Yen, Jing-Yuan Chuang, Hsin-Ling Yang
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Antioxidants
Subjects:
ectoine
keratinocytes
melanogenesis
tyrosinase
α-msh
nrf2
Online Access:https://www.mdpi.com/2076-3921/9/1/63

Internet

https://www.mdpi.com/2076-3921/9/1/63

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