Pioglitazone does not synergize with mirabegron to increase beige fat or further improve glucose metabolism

Pioglitazone does not synergize with mirabegron to increase beige fat or further improve glucose metabolism

BACKGROUND Beige and brown adipose tissue (BAT) are associated with improved metabolic homeostasis. We recently reported that the β3-adrenergic receptor agonist mirabegron induced beige adipose tissue in obese insulin-resistant subjects, and this was accompanied by improved glucose metabolism. Here...

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Bibliographic Details
Main Authors: Brian S. Finlin, Hasiyet Memetimin, Beibei Zhu, Amy L. Confides, Hemendra J. Vekaria, Riham H. El Khouli, Zachary R. Johnson, Philip M. Westgate, Jianzhong Chen, Andrew J. Morris, Patrick G. Sullivan, Esther E. Dupont-Versteegden, Philip A. Kern
Format: Article
Language:English
Published: American Society for Clinical investigation 2021-03-01
Series:JCI Insight
Subjects:
Clinical trials
Metabolism
Online Access:https://doi.org/10.1172/jci.insight.143650

Internet

https://doi.org/10.1172/jci.insight.143650

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