A possible role for selenoprotein glutathione peroxidase (GPx1) and thioredoxin reductases (TrxR1) in thyroid cancer: our experience in thyroid surgery

A possible role for selenoprotein glutathione peroxidase (GPx1) and thioredoxin reductases (TrxR1) in thyroid cancer: our experience in thyroid surgery

Abstract Background Oxidative stress is responsible for some alterations in the chemical structure and, consequently, in the function of proteins, lipids, and DNA. Recent studies have linked oxidative stress to cancers, particularly thyroid cancer, but the mechanisms remain unclear. Here, we further...

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Bibliographic Details
Main Authors: Alessio Metere, Francesca Frezzotti, Claire Elizabeth Graves, Massimo Vergine, Alessandro De Luca, Donatella Pietraforte, Laura Giacomelli
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Cancer Cell International
Subjects:
Oxidative stress
Thyroid cancer
Glutathione peroxidase (GPx1)
Thioredoxin reductases (TrxR1)
Selenium enzymes
Online Access:http://link.springer.com/article/10.1186/s12935-018-0504-4

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http://link.springer.com/article/10.1186/s12935-018-0504-4

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