WAVE2 Regulates Actin-Dependent Processes Induced by the B Cell Antigen Receptor and Integrins

WAVE2 Regulates Actin-Dependent Processes Induced by the B Cell Antigen Receptor and Integrins

B cell antigen receptor (BCR) signaling induces actin cytoskeleton remodeling by stimulating actin severing, actin polymerization, and the nucleation of branched actin networks via the Arp2/3 complex. This enables B cells to spread on antigen-bearing surfaces in order to increase antigen encounters...

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Bibliographic Details
Main Authors: Abhishek Bedi, Kate Choi, Connor Keane, Madison Bolger-Munro, Ashley R. Ambrose, Michael R. Gold
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Cells
Subjects:
B cell
B cell antigen receptor (BCR)
antigen presenting cell (APC)
F-actin
WAVE2
Arp2/3 complex
Online Access:https://www.mdpi.com/2073-4409/12/23/2704

Internet

https://www.mdpi.com/2073-4409/12/23/2704

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