MAPKs/AP-1, not NF-κB, is responsible for MCP-1 production in TNF-α-activated adipocytes
Obesity is associated with the infiltration of monocytes/macrophages into adipose tissue in which MCP-1 plays a crucial role. But the regulatory mechanism of MCP-1 expression in adipocytes is not well defined. Our results demonstrated that TNF-α induced abundant MCP-1 production in adipocytes, inclu...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2022-12-01
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Series: | Adipocyte |
Subjects: | |
Online Access: | https://www.tandfonline.com/doi/10.1080/21623945.2022.2107786 |