The activation of GABAergic neurons in the hypothalamic tuberomammillary nucleus attenuates sevoflurane and propofol-induced anesthesia in mice

The activation of GABAergic neurons in the hypothalamic tuberomammillary nucleus attenuates sevoflurane and propofol-induced anesthesia in mice

Background: The histaminergic neurons in the hypothalamic tuberomammillary nucleus (TMN) have been suggested to play a vital role in maintaining a rising state. But the neuronal types of the TMN are in debate and the role of GABAergic neurons remains unclear.Methods: In the present study, we examine...

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Bibliographic Details
Main Authors: Jing Liu, Xiao Liu, Wen-Yu Zhou, Jun Gan, Jie Wang, Qi Zhang, Jun-Liang Li, Zhong-Shan Shen, Yue-Ying Zhang, Qiong-Yao Tang, Zhe Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Pharmacology
Subjects:
sevoflurane
propofol
hypothalamic tuberomammillary nucleus
gabaergic neurons
anesthesia
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1153735/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1153735/full

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