Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis

Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease and adult lung spheroid cells have been shown to promote regeneration in animal models of IPF. Here the authors show that the secretome and exosomes of lung spheroid cells is effective as inhalation treatment in rodent models of lung injury...

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Bibliographic Details
Main Authors: Phuong-Uyen C. Dinh, Dipti Paudel, Hayden Brochu, Kristen D. Popowski, M. Cyndell Gracieux, Jhon Cores, Ke Huang, M. Taylor Hensley, Erin Harrell, Adam C. Vandergriff, Arianna K. George, Raina T. Barrio, Shiqi Hu, Tyler A. Allen, Kevin Blackburn, Thomas G. Caranasos, Xinxia Peng, Lauren V. Schnabel, Kenneth B. Adler, Leonard J. Lobo, Michael B. Goshe, Ke Cheng
Format: Article
Language:English
Published: Nature Portfolio 2020-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-14344-7

Internet

https://doi.org/10.1038/s41467-020-14344-7

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