Cerebral endothelial cell derived small extracellular vesicles improve cognitive function in aged diabetic rats

Small extracellular vesicles (sEVs) mediate cell-cell communication by transferring their cargo biological materials into recipient cells. Diabetes mellitus (DM) induces cerebral vascular dysfunction and neurogenesis impairment, which are associated with cognitive decline and an increased risk of de...

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Bibliographic Details
Main Authors: Li Zhang, Chao Li, Rui Huang, Hua Teng, Yi Zhang, Min Zhou, Xiangshuang Liu, Baoyan Fan, Hao Luo, Annie He, Anna Zhao, Mei Lu, Michael Chopp, Zheng Gang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.926485/full