Transcriptome-guided metabolic network analysis reveals rearrangements of carbon flux distribution in Neisseria gonorrhoeae during neutrophil co-culture

Transcriptome-guided metabolic network analysis reveals rearrangements of carbon flux distribution in Neisseria gonorrhoeae during neutrophil co-culture

ABSTRACT The ability of bacterial pathogens to metabolically adapt to the environmental conditions of their hosts is critical to both colonization and invasive disease. Infection with Neisseria gonorrhoeae (the gonococcus, Gc) is characterized by the influx of neutrophils [polymorphonuclear leukocyt...

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Bibliographic Details
Main Authors: Aimee D. Potter, Christopher M. Baiocco, Jason A. Papin, Alison K. Criss
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:mSystems
Subjects:
metabolism
Neisseria gonorrhoeae
genome-scale metabolic network reconstruction
transcriptomics
neutrophils
metabolic network analysis
Online Access:https://journals.asm.org/doi/10.1128/msystems.01265-22

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https://journals.asm.org/doi/10.1128/msystems.01265-22

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