Multi-site desmoplastic small round cell tumors are genetically related and immune-cold

Multi-site desmoplastic small round cell tumors are genetically related and immune-cold

Abstract Desmoplastic small round cell tumor (DSRCT) is a highly aggressive soft tissue sarcoma that is characterized by the EWSR1-WT1 fusion protein. Patients present with hundreds of tumor implants in their abdominal cavity at various sites. To determine the genetic relatedness among these sites,...

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Bibliographic Details
Main Authors: Chia-Chin Wu, Hannah C. Beird, Salah-Eddine Lamhamedi-Cherradi, Melinda Soeung, Davis Ingram, Danh D. Truong, Robert W. Porter, Sandhya Krishnan, Latasha Little, Curtis Gumbs, Jianhua Zhang, Mark Titus, Giannicola Genovese, Joseph A. Ludwig, Alexander J. Lazar, Andrea Hayes-Jordan, P. Andrew Futreal
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-022-00257-9

Internet

https://doi.org/10.1038/s41698-022-00257-9

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