Changes in cGMP levels affect the localization of EGL-4 in AWC in Caenorhabditis elegans.

The Protein Kinase G, EGL-4, is required within the C. elegans AWC sensory neurons to promote olfactory adaptation. After prolonged stimulation of these neurons, EGL-4 translocates from the cytosol to the nuclei of the AWC. This nuclear translocation event is both necessary and sufficient for adapta...

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Bibliographic Details
Main Authors: Damien M O'Halloran, O Scott Hamilton, Jin I Lee, Maria Gallegos, Noelle D L'Etoile
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3272044?pdf=render