Plasmodium berghei leucine-rich repeat protein 1 downregulates protein phosphatase 1 activity and is required for efficient oocyst development

Plasmodium berghei leucine-rich repeat protein 1 downregulates protein phosphatase 1 activity and is required for efficient oocyst development

Protein phosphatase 1 (PP1) is a key enzyme for Plasmodium development. However, the detailed mechanisms underlying its regulation remain to be deciphered. Here, we report the functional characterization of the Plasmodium berghei leucine-rich repeat protein 1 (PbLRR1), an orthologue of SDS22, one of...

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Bibliographic Details
Main Authors: Aline Fréville, Bénédicte Gnangnon, Annie Z. Tremp, Caroline De Witte, Katia Cailliau, Alain Martoriati, El Moukthar Aliouat, Priyanka Fernandes, Cerina Chhuon, Olivier Silvie, Sabrina Marion, Ida Chiara Guerrera, Johannes T. Dessens, Christine Pierrot, Jamal Khalife
Format: Article
Language:English
Published: The Royal Society 2022-08-01
Series:Open Biology
Subjects:
leucine-rich repeat protein 1
SDS22
protein phosphatase 1
PP1
inhibitor 3
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsob.220015

Internet

https://royalsocietypublishing.org/doi/10.1098/rsob.220015

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