The Potential Role of Lysosomal Sequestration in Sunitinib Resistance of Renal Cell Cancer
Renal cell carcinoma (RCC) is a highly vascularized tumor type, which is often associated with inactivated mutations in the von Hippel-Lindau gene that drives proangiogenic signaling pathways. As such, new therapies for the treatment of RCC have largely been focused on blocking angiogenesis. Sunitin...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Codon Publications
2016-01-01
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| Series: | Journal of Kidney Cancer and VHL |
| Subjects: | |
| Online Access: | https://jkcvhl.com/index.php/jkcvhl/article/view/44 |