Structure of HIV-2 Nef Reveals Features Distinct from HIV-1 Involved in Immune Regulation

Structure of HIV-2 Nef Reveals Features Distinct from HIV-1 Involved in Immune Regulation

Summary: The human immunodeficiency virus (HIV) accessory protein Nef plays a major role in establishing and maintaining infection, particularly through immune evasion. Many HIV-2-infected people experience long-term viral control and survival, resembling HIV-1 elite control. HIV-2 Nef has overlappi...

Full description

Bibliographic Details
Main Authors: Kengo Hirao, Sophie Andrews, Kimiko Kuroki, Hiroki Kusaka, Takashi Tadokoro, Shunsuke Kita, Toyoyuki Ose, Sarah L. Rowland-Jones, Katsumi Maenaka
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004219305036

Internet

http://www.sciencedirect.com/science/article/pii/S2589004219305036

Similar Items