CRL4DCAF8 Ubiquitin Ligase Targets Histone H3K79 and Promotes H3K9 Methylation in the Liver

CRL4DCAF8 Ubiquitin Ligase Targets Histone H3K79 and Promotes H3K9 Methylation in the Liver

Transcription from chromosomes is regulated by posttranslational modifications to histones, such as methylation and ubiquitination. Monoubiquitination of histones H2A and H2B influences H3 methylation to reinforce the activation or repression of gene expression. Here, we provide evidence that H3 pol...

Full description

Bibliographic Details
Main Authors: Gaofeng Li, Tong Ji, Jiang Chen, Yufei Fu, Lidan Hou, Yan Feng, Tingyue Zhang, Tianyu Song, Jie Zhao, Yoko Endo, Hui Lin, Xiujun Cai, Yong Cang
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Cell Reports
Subjects:
CRL4
DDB1
DCAF8
H3 ubiquitination
liver maturation
H3K9 methylation
AFP
GPC3
H19
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717300943

Internet

http://www.sciencedirect.com/science/article/pii/S2211124717300943

Similar Items