Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes

The Transient Receptor Potential Vanilloid 2 (TRPV2) channel is a member of the temperature-sensing thermoTRPV family. Recent advances in cryo-electronmicroscopy (cryo-EM) and X-ray crystallography have provided many important insights into the gating mechanisms of thermoTRPV channels. Interestingly...

Full description

Bibliographic Details
Main Authors: Lejla Zubcevic, Allen L Hsu, Mario J Borgnia, Seok-Yong Lee
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-05-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/45779