Dilated cardiomyopathy-mediated heart failure induces a unique skeletal muscle myopathy with inflammation

Abstract Background Skeletal muscle myopathy and exercise intolerance are diagnostic hallmarks of heart failure (HF). However, the molecular adaptations of skeletal muscles during dilated cardiomyopathy (DCM)-mediated HF are not completely understood. Methods Skeletal muscle structure and function w...

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Bibliographic Details
Main Authors: Taejeong Song, Palanikumar Manoharan, Douglas P. Millay, Sheryl E. Koch, Jack Rubinstein, Judith A. Heiny, Sakthivel Sadayappan
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Skeletal Muscle
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13395-019-0189-y