Central role of Prominin-1 in lipid rafts during liver regeneration

Bahn et al explore the role of the lipid raft protein Prominin-1 in liver regeneration. They show that Prominin-1 promotes hepatocyte proliferation after acute liver injury by interacting with the signal transducer GP130, confining it to lipid rafts and activating IL-6 signaling pathway and eventual...

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Bibliographic Details
Main Authors: Myeong-Suk Bahn, Dong-Min Yu, Myoungwoo Lee, Sung-Je Jo, Ji-Won Lee, Ho-Chul Kim, Hyun Lee, Hong Lim Kim, Arum Kim, Jeong-Ho Hong, Jun Seok Kim, Seung-Hoi Koo, Jae-Seon Lee, Young-Gyu Ko
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-33969-4