Central role of Prominin-1 in lipid rafts during liver regeneration
Bahn et al explore the role of the lipid raft protein Prominin-1 in liver regeneration. They show that Prominin-1 promotes hepatocyte proliferation after acute liver injury by interacting with the signal transducer GP130, confining it to lipid rafts and activating IL-6 signaling pathway and eventual...
Main Authors: | , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-10-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-33969-4 |