Tuning Enzymatically Crosslinked Silk Fibroin Hydrogel Properties for the Development of a Colorectal Cancer Extravasation 3D Model on a Chip

Abstract Microfluidic devices are now the most promising tool to mimic in vivo like scenarios such as tumorigenesis and metastasis due to its ability to more closely mimic cell's natural microenvironment (such as 3D environment and continuous perfusion of nutrients). In this study, the ability...

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Bibliographic Details
Main Authors: Mariana R. Carvalho, Fátima Raquel Maia, Sílvia Vieira, Rui L. Reis, Joaquim M. Oliveira
Format: Article
Language:English
Published: Wiley 2018-06-01
Series:Global Challenges
Subjects:
Online Access:https://doi.org/10.1002/gch2.201700100