Regular use of proton-pump inhibitors and risk of stroke: a population-based cohort study and meta-analysis of randomized-controlled trials

Abstract Background Although randomized controlled trials (RCTs) have suggested a non-significant increased risk of stroke among proton pump inhibitor (PPI) users, the association has not been confirmed. We evaluated the association between regular use of PPIs and incident stroke and identified popu...

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Bibliographic Details
Main Authors: Man Yang, Qiangsheng He, Fang Gao, Krish Nirantharakumar, Tonny Veenith, Xiwen Qin, Amy T. Page, Martin C. S. Wong, Junjie Huang, Zi Chong Kuo, Bin Xia, Changhua Zhang, Yulong He, Wenbo Meng, Jinqiu Yuan, Yihang Pan
Format: Article
Language:English
Published: BMC 2021-12-01
Series:BMC Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12916-021-02180-5