Evaluation on the efficacy and immunogenicity of recombinant DNA plasmids expressing spike genes from porcine transmissible gastroenteritis virus and porcine epidemic diarrhea virus.

Evaluation on the efficacy and immunogenicity of recombinant DNA plasmids expressing spike genes from porcine transmissible gastroenteritis virus and porcine epidemic diarrhea virus.

Porcine transmissible gastroenteritis virus (TGEV) and porcine epidemic diarrhea virus (PDEV) can cause severe diarrhea in pigs. Development of effective vaccines against TGEV and PEDV is one of important prevention measures. The spike (S) protein is the surface glycoprotein of TGEV and PEDV, which...

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Bibliographic Details
Main Authors: Fandan Meng, Yudong Ren, Siqingaowa Suo, Xuejiao Sun, Xunliang Li, Pengchong Li, Wei Yang, Guangxing Li, Lu Li, Christel Schwegmann-Wessels, Georg Herrler, Xiaofeng Ren
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3602451?pdf=render

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http://europepmc.org/articles/PMC3602451?pdf=render

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