Transcription of <i>HOX</i> Genes Is Significantly Increased during Neuronal Differentiation of iPSCs Derived from Patients with Parkinson’s Disease

Transcription of <i>HOX</i> Genes Is Significantly Increased during Neuronal Differentiation of iPSCs Derived from Patients with Parkinson’s Disease

Parkinson’s disease (PD) is the most serious movement disorder, but the actual cause of this disease is still unknown. Induced pluripotent stem cell-derived neural cultures from PD patients carry the potential for experimental modeling of underlying molecular events. We analyzed the RNA-seq data of...

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Bibliographic Details
Main Authors: Viya B. Fedoseyeva, Ekaterina V. Novosadova, Valentina V. Nenasheva, Lyudmila V. Novosadova, Igor A. Grivennikov, Vyacheslav Z. Tarantul
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Journal of Developmental Biology
Subjects:
Parkinson’s disease
induced pluripotent stem cells
neural precursor cells
terminally differentiated neurons
RNA-seq
<i>HOX</i> genes
Online Access:https://www.mdpi.com/2221-3759/11/2/23

Internet

https://www.mdpi.com/2221-3759/11/2/23

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