Immune system-related plasma extracellular vesicles in healthy aging

ObjectivesTo identify age-related plasma extracellular vehicle (EVs) phenotypes in healthy adults.MethodsEV proteomics by high-resolution mass spectrometry to evaluate EV protein stability and discover age-associated EV proteins (n=4 with 4 serial freeze-thaws each); validation by high-resolution fl...

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Bibliographic Details
Main Authors: Xin Zhang, Sisi Ma, Janet L. Huebner, Syeda Iffat Naz, Noor Alnemer, Erik J. Soderblom, Constantin Aliferis, Virginia Byers Kraus
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1355380/full