Longitudinal temperature measurement can determine humane endpoints in BALB/c mouse models of ESKAPEE infection

Longitudinal temperature measurement can determine humane endpoints in BALB/c mouse models of ESKAPEE infection

ABSTRACTAntimicrobial resistance (AMR) is a worldwide problem, which is driving more preclinical research to find new treatments and countermeasures for drug-resistant bacteria. However, translational models in the preclinical space have remained static for years. To improve animal use ethical consi...

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Bibliographic Details
Main Authors: Randal Scott Dudis, Ting Y. Wong, Mariel G. Escatte, Yonas A. Alamneh, Rania Abu-Taleb, Wanwen Su, Christine Czintos, Timothy A. Fitzgerald, Yoann Le Breton, Daniel V. Zurawski
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Virulence
Subjects:
Temperature
ESKAPEE
murine pulmonary infection model
BALB/c
humane endpoints
replacement, reduction, refinement (3Rs)
Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2023.2186331

Internet

https://www.tandfonline.com/doi/10.1080/21505594.2023.2186331

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