Sacubitril and valsartan protect from experimental myocardial infarction by ameliorating oxidative damage in Wistar rats

Sacubitril and valsartan protect from experimental myocardial infarction by ameliorating oxidative damage in Wistar rats

Background: Sacubitril (SAC), a neprilysin inhibitor prevent degradation of neprilysin and activate cGMP signaling pathways leading to rise in blood volume concurrent to blood pressure by means of vasoactive peptides, adrenomedullin, and bradykinin. Objective: The aim of this study was to evaluate t...

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Bibliographic Details
Main Authors: Mohd Imran, Md Quamrul Hassan, Md Sayeed Akhtar, Obaid Rahman, M. Akhtar, Abul Kalam Najmi
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Clinical and Experimental Hypertension
Subjects:
aneprilysin inhibitor
oxidative damage
sacubitril
valsartan
isoproterenol
myocardial infarction
Online Access:http://dx.doi.org/10.1080/10641963.2018.1441862

Internet

http://dx.doi.org/10.1080/10641963.2018.1441862

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