Determination of Intra- and Extracellular Metabolic Adaptations of 3D Cell Cultures upon Challenges in Real-Time by NMR

Determination of Intra- and Extracellular Metabolic Adaptations of 3D Cell Cultures upon Challenges in Real-Time by NMR

NMR flow devices provide longitudinal real-time quantitative metabolome characterisation of living cells. However, discrimination of intra- and extracellular contributions to the spectra represents a major challenge in metabolomic NMR studies. The present NMR study demonstrates the possibility to qu...

Full description

Bibliographic Details
Main Authors: Christian Urzì, Damian Hertig, Christoph Meyer, Sally Maddah, Jean-Marc Nuoffer, Peter Vermathen
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
NMR
bioreactor
fibroblasts
metabolomic
diffusion
intracellular fingerprints
Online Access:https://www.mdpi.com/1422-0067/23/12/6555

Internet

https://www.mdpi.com/1422-0067/23/12/6555

Similar Items