Runx2 Regulates <i>Galnt3</i> and <i>Fgf23</i> Expressions and Galnt3 Decelerates Osteoid Mineralization by Stabilizing Fgf23

Runx2 Regulates <i>Galnt3</i> and <i>Fgf23</i> Expressions and Galnt3 Decelerates Osteoid Mineralization by Stabilizing Fgf23

Runx2 (runt related transcription factor 2) is an essential transcription factor for osteoblast proliferation and differentiation. Uridine diphosphate (UDP)-N-acetylgalactosamine (GalNAc): polypeptide GalNAc-transferase 3 (Galnt3) prevents proteolytic processing of fibroblast growth factor 23 (Fgf23...

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Bibliographic Details
Main Authors: Qing Jiang, Xin Qin, Takeshi Moriishi, Ryo Fukuyama, Shinichi Katsumata, Hiroshi Matsuzaki, Hisato Komori, Yuki Matsuo, Chiharu Sakane, Kosei Ito, Hironori Hojo, Shinsuke Ohba, Toshihisa Komori
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
Runx2
Galnt3
Fgf23
osteocyte
phosphorus
hyperphosphatemia
Online Access:https://www.mdpi.com/1422-0067/25/4/2275

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https://www.mdpi.com/1422-0067/25/4/2275

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