Genetic factors modulate the impact of pubertal androgen excess on insulin sensitivity and fertility.

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder of reproductive age women. The syndrome is caused by a combination of environmental influences and genetic predisposition. Despite extensive efforts, the heritable factors contributing to PCOS development are not fully understood...

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Bibliographic Details
Main Authors: Abigail R Dowling, Laura B Nedorezov, Xiaoliang Qiu, Joseph S Marino, Jennifer W Hill
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3835926?pdf=render