Epigenetic alterations in the brain associated with HIV-1 infection and methamphetamine dependence.

Epigenetic alterations in the brain associated with HIV-1 infection and methamphetamine dependence.

HIV involvement of the CNS continues to be a significant problem despite successful use of combination antiretroviral therapy (cART). Drugs of abuse can act in concert with HIV proteins to damage glia and neurons, worsening the neurotoxicity caused by HIV alone. Methamphetamine (METH) is a highly ad...

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Bibliographic Details
Main Authors: Paula Desplats, Wilmar Dumaop, Peter Cronin, Sara Gianella, Steven Woods, Scott Letendre, David Smith, Eliezer Masliah, Igor Grant
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4108358?pdf=render

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http://europepmc.org/articles/PMC4108358?pdf=render

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