Anti-EGFR anchored paclitaxel loaded PLGA nanoparticles for the treatment of triple negative breast cancer. In-vitro and in-vivo anticancer activities.

Anti-EGFR anchored paclitaxel loaded PLGA nanoparticles for the treatment of triple negative breast cancer. In-vitro and in-vivo anticancer activities.

The aim of the present study is to analyze the viability of anti-EGFR anchored immunonanoparticle (INP) bearing Paclitaxel (PTX) to specifically bind the EGFR protein on the TNBC cells. The NP was prepared by nanoprecipitation and characterized the particle size, charge, entrapment of drug and relea...

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Bibliographic Details
Main Authors: Vijayan Venugopal, Shalini Krishnan, Vasanth Raj Palanimuthu, Subin Sankarankutty, Jayaraja Kumar Kalaimani, Sundram Karupiah, Ng Siew Kit, Tang Thean Hock
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6224030?pdf=render

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http://europepmc.org/articles/PMC6224030?pdf=render

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