Genotypic and phenotypic mechanisms underlying antimicrobial resistance and synergistic efficacy of rifampicin-based combinations against carbapenem-resistant Acinetobacter baumannii

Genotypic and phenotypic mechanisms underlying antimicrobial resistance and synergistic efficacy of rifampicin-based combinations against carbapenem-resistant Acinetobacter baumannii

Purpose: Carbapenem-resistant Acinetobacter baumannii (CRAB) is an urgent concern to public health. This study focuses on exploring the resistance mechanisms and the in vitro results of using rifampicin in combination with conventional antibiotics for the management of CRAB. Methods: The synergistic...

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Bibliographic Details
Main Authors: Lois Chinwe Nwabor, Arnon Chukamnerd, Ozioma Forstinus Nwabor, Komwit Surachat, Rattanaruji Pomwised, Kongpop Jeenkeawpiam, Sarunyou Chusri
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Heliyon
Subjects:
Carbapenem-resistant Acinetobacter baumannii
Whole genome sequencing
Antimicrobial resistance
Efflux pump
Rifampicin
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024033577

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http://www.sciencedirect.com/science/article/pii/S2405844024033577

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