Airway basal cells show regionally distinct potential to undergo metaplastic differentiation

Airway basal cells show regionally distinct potential to undergo metaplastic differentiation

Basal cells are multipotent stem cells of a variety of organs, including the respiratory tract, where they are major components of the airway epithelium. However, it remains unclear how diverse basal cells are and how distinct subpopulations respond to airway challenges. Using single cell RNA-sequen...

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Bibliographic Details
Main Authors: Yizhuo Zhou, Ying Yang, Lihao Guo, Jun Qian, Jian Ge, Debora Sinner, Hongxu Ding, Andrea Califano, Wellington V Cardoso
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-09-01
Series:eLife
Subjects:
basal cell heterogeneity
stem cell
organotypic cultures
lung repair
airway epithelium
Online Access:https://elifesciences.org/articles/80083

Internet

https://elifesciences.org/articles/80083

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