Comprehensive characterization of clonality of driver genes revealing their clinical relevance in colorectal cancer

Comprehensive characterization of clonality of driver genes revealing their clinical relevance in colorectal cancer

Abstract Background Genomic studies of colorectal cancer have revealed the complex genomic heterogeneity of the tumor. The acquisition and selection of genomic alterations may be critical to understanding the initiation and progression of this disease. Methods In this study, we have systematically c...

Full description

Bibliographic Details
Main Authors: Jian Shi, Li Wang, Xiangzhe Yin, Lixia Wang, Lin Bo, Kailai Liu, Ke Feng, Shihua Lin, Yanjun Xu, Shangwei Ning, Hongying Zhao
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Journal of Translational Medicine
Subjects:
Subclonal mutation
Clonal mutation
Prognostic biomarkers
Driver genes
Immune evasion
Colorectal cancer
Online Access:https://doi.org/10.1186/s12967-022-03529-x

Internet

https://doi.org/10.1186/s12967-022-03529-x

Similar Items