Residues in the 1st Transmembrane-Spanning Helix Are Important for GABA<sub>A</sub><i>ρ</i> Receptor Function

GABA<sub>A</sub><i>ρ</i> receptors are a subfamily of the GABA<sub>A</sub> receptor family of pentameric ligand-gated ion channels (pLGICs). Each subunit has a common structure, including a transmembrane domain of four α-helices (M1–M4). The aim of this study was...

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Bibliographic Details
Main Authors: Kate M. Crowther, Susanne M. Mesoy, Sarah C. R. Lummis
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/12/9/1251