Molecular and Functional Analysis of Sunitinib-Resistance Induction in Human Renal Cell Carcinoma Cells

Molecular and Functional Analysis of Sunitinib-Resistance Induction in Human Renal Cell Carcinoma Cells

Resistance in clear cell renal cell carcinoma (ccRCC) against sunitinib is a multifaceted process encompassing numerous molecular aberrations. This induces clinical complications, reducing the treatment success. Understanding these aberrations helps us to select an adapted treatment strategy that su...

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Bibliographic Details
Main Authors: Magdalena Rausch, Adriano Rutz, Pierre-Marie Allard, Céline Delucinge-Vivier, Mylène Docquier, Olivier Dormond, Jean-Luc Wolfender, Patrycja Nowak-Sliwinska
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
acquired drug resistance
(clear cell) renal cell carcinoma
drug combination
isomerization
metabolites
sunitinib
Online Access:https://www.mdpi.com/1422-0067/22/12/6467

Internet

https://www.mdpi.com/1422-0067/22/12/6467

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