Single-cell analysis of immune cell transcriptome during HIV-1 infection and therapy

Abstract Background Cellular immune responses are phenotypically and functionally perturbed during HIV-1 infection, with the majority of function restored upon antiretroviral therapy (ART). Despite ART, residual inflammation remains that can lead to HIV-related co-morbidities and mortality, indicati...

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Bibliographic Details
Main Authors: Justin Pollara, Santosh Khanal, R. Whitney Edwards, Bhavna Hora, Guido Ferrari, Barton F. Haynes, Todd Bradley
Format: Article
Language:English
Published: BMC 2022-09-01
Series:BMC Immunology
Subjects:
Online Access:https://doi.org/10.1186/s12865-022-00523-2