Intracellular Major Histocompatibility Complex Class II and C-X-C Motif Chemokine Ligand 10-Expressing Neutrophils Indicate the State of Anti-Tumor Activity Induced by <i>Bacillus Calmette–Guérin</i>

Intracellular Major Histocompatibility Complex Class II and C-X-C Motif Chemokine Ligand 10-Expressing Neutrophils Indicate the State of Anti-Tumor Activity Induced by <i>Bacillus Calmette–Guérin</i>

(1) Background: Inflammatory responses induce the formation of both anti-tumor and pro-tumor neutrophils known as myeloid-derived suppressor cells (MDSCs). Intermittent intravesical infusion of <i>Bacillus Calmette–Guérin</i> (BCG) is an established cancer immunotherapy for non-muscle-in...

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Bibliographic Details
Main Authors: Yuji Takeda, Tomoyuki Kato, Saima Sabrina, Sei Naito, Hiromi Ito, Naoto Emi, Yuya Kuboki, Yuki Takai, Hiroki Fukuhara, Masaki Ushijima, Takafumi Narisawa, Mayu Yagi, Hidenori Kanno, Toshihiko Sakurai, Hayato Nishida, Akemi Araki, Yoshitaka Shimotai, Mikako Nagashima, Yusuke Nouchi, Shinichi Saitoh, Hidetoshi Nara, Norihiko Tsuchiya, Hironobu Asao
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Biomedicines
Subjects:
<i>Bacillus Calmette–Guérin</i> (BCG)
bladder cancer
C-X-C motif chemokine ligand 10 (CXCL10)
major histocompatibility complex (MHC) class II
myeloid-derived suppressor cells (MDSCs)
neutrophils
Online Access:https://www.mdpi.com/2227-9059/11/11/3062

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https://www.mdpi.com/2227-9059/11/11/3062

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