Loxhd1b inhibits the hair cell development in zebrafish: Possible relation to the BDNF/TrkB/ERK pathway

Loxhd1b inhibits the hair cell development in zebrafish: Possible relation to the BDNF/TrkB/ERK pathway

BackgroundMutations in lipoxygenase homology domain 1 (LOXHD1) cause autosomal recessive inheritance, leading to high-frequency and intermediate-frequency hearing losses in patients. To date, studies on the localization of LOXHD1 gene expression are limited. In this study, we aimed to observe the ex...

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Bibliographic Details
Main Authors: Jingwen Liu, Xu Zhang, Qingchen Zhang, Rongrong Wang, Jingyu Ma, Xiaohui Bai, Dawei Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
zebrafish
hair cell
Loxhd1b
BDNF/TrkB/ERK signaling pathway
morpholino
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2022.1065309/full

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https://www.frontiersin.org/articles/10.3389/fncel.2022.1065309/full

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