Evaluation of Safety and Potency of Kyasanur Forest Disease (KFD) Vaccine Inactivated with Different Concentrations of Formalin and Comparative Evaluation of In Vitro and In Vivo Methods of Virus Titration in KFD Vaccine

Evaluation of Safety and Potency of Kyasanur Forest Disease (KFD) Vaccine Inactivated with Different Concentrations of Formalin and Comparative Evaluation of In Vitro and In Vivo Methods of Virus Titration in KFD Vaccine

We evaluated the safety and potency of the Kyasanur Forest disease (KFD) vaccine inactivated with different formalin concentrations in mice, since the side effects due to higher formalin concentrations have been a major reason for vaccine refusal. Furthermore, with an objective to reduce the use of...

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Bibliographic Details
Main Authors: Ullas Gowda K. Srikanth, Chandranaik B. Marinaik, Amitha Reena Gomes, Doddamane Rathnamma, Sonnahallipura M. Byregowda, Shrikrishna Isloor, Archana Munivenkatarayappa, Mudalagiri D. Venkatesha, Suguna Rao, Apsana Rizwan, Raveendra Hegde
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Biomedicines
Subjects:
kyasanur forest disease
kyasanur forest disease virus
KFD
KFD vaccine
formalin
real-time PCR
Online Access:https://www.mdpi.com/2227-9059/11/7/1871

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https://www.mdpi.com/2227-9059/11/7/1871

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