Age-Associated Lipidome Changes in Metaphase II Mouse Oocytes.

The quality of mammalian oocytes declines with age, which negatively affects fertilization and developmental potential. The aging process often accompanies damages to macromolecules such as proteins, DNA, and lipids. To investigate if aged oocytes display an altered lipidome compared to young oocyte...

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Bibliographic Details
Main Authors: Hyuck Jun Mok, Hyejin Shin, Jae Won Lee, Geun-Kyung Lee, Chang Suk Suh, Kwang Pyo Kim, Hyunjung Jade Lim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4755615?pdf=render