An osteoarthritis subtype characterized by synovial lipid metabolism disorder and fibroblast-like synoviocyte dysfunction

An osteoarthritis subtype characterized by synovial lipid metabolism disorder and fibroblast-like synoviocyte dysfunction

Background: The heterogeneity of osteoarthritis (OA) significantly limits the effectiveness of pharmacological treatments in an unselected patient population. In this context, the identification of OA subtypes is meaningful for the development of therapies that target specific types of OA pathogenes...

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Bibliographic Details
Main Authors: Xu Cao, Zhi Cui, Zhiyu Ding, Yong Chen, Song Wu, Xinxing Wang, Junjie Huang
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Journal of Orthopaedic Translation
Subjects:
Adenylyl cyclase 7
Osteoarthritis
Disease type
Fibroblast-like synoviocytes
Epithelial-mesenchymal transition
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X22000110

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http://www.sciencedirect.com/science/article/pii/S2214031X22000110

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