Immunopathological basis of immune-related adverse events induced by immune checkpoint blockade therapy

Despite the considerable success of cancer immunotherapy with immune checkpoint inhibitors, their nonspecific release of the immunosuppressive mechanism is often associated with immune-related adverse events (irAEs). irAEs significantly disturb patients’ quality of life and can even be life-threaten...

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Bibliographic Details
Main Authors: Terufumi Kubo, Yoshihiko Hirohashi, Tomohide Tsukahara, Takayuki Kanaseki, Kenji Murata, Rena Morita, Toshihiko Torigoe
Format: Article
Language:English
Published: Taylor & Francis Group 2021-09-01
Series:Immunological Medicine
Subjects:
Online Access:http://dx.doi.org/10.1080/25785826.2021.1976942