Recent Advances in Studying Interfacial Adsorption of Bioengineered Monoclonal Antibodies

Recent Advances in Studying Interfacial Adsorption of Bioengineered Monoclonal Antibodies

Monoclonal antibodies (mAbs) are an important class of biotherapeutics; as of 2020, dozens are commercialized medicines, over a hundred are in clinical trials, and many more are in preclinical developmental stages. Therapeutic mAbs are sequence modified from the wild type IgG isoforms to varying ext...

Full description

Bibliographic Details
Main Authors: Peter Hollowell, Zongyi Li, Xuzhi Hu, Sean Ruane, Cavan Kalonia, Christopher F. van der Walle, Jian R. Lu
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Molecules
Subjects:
mAbs
surface adsorption
co-adsorption
antibody
structural unfolding
self-assembly
Online Access:https://www.mdpi.com/1420-3049/25/9/2047

Internet

https://www.mdpi.com/1420-3049/25/9/2047

Similar Items