Maximum entropy reconstructions of dynamic signaling networks from quantitative proteomics data.

Advances in mass spectrometry among other technologies have allowed for quantitative, reproducible, proteome-wide measurements of levels of phosphorylation as signals propagate through complex networks in response to external stimuli under different conditions. However, computational approaches to i...

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Bibliographic Details
Main Authors: Jason W Locasale, Alejandro Wolf-Yadlin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2728537?pdf=render